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Sunday sees the initial Wear-Tyne derby since 2024, but which side will celebrate – Sunderland or Newcastle?
"Throughout the majority of last season, it was unthinkable the Wearside club earning promotion and holding their own with Eddie Howe's Newcastle, never mind being above them in the table," stated analyst Chris Sutton.
"Things are very different now, and the way Sunderland play leads me to believe they've got a solid shot."
He is offering predictions for all 380 Premier League games this campaign, against AI, readers and a assortment of guests.
For this weekend's fixtures, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the eLions – the Football Association's official esports team – at the gaming title Uefa eEuro 2025 finals tournament, which takes place at Twickenham Stadium on Saturday.
You can watch Uefa's YouTube, Instagram Live and short-form video channels, as well as the official Twitch channel and YouTube and the national team's Twitch.
Do you agree with their predictions? Share your own predictions below.
The fan-favourite scoreline chosen for each game is used in the leaderboards at the foot of this page.
A correct result (choosing a win, draw or defeat) is worth ten points. An accurate scoreline earns 40 points.
Ray, who also plays Gen City and Manchester City as well as England, is making his debut at the eEuros finals after getting through the qualifying.
Eight players will represent their nations at the finals in a straight knockout, playing for a six-figure prize fund and a prestigious spot in the global championship qualifiers, with the Danish representative Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray said. "I have a really good coach alongside me and preparation has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you fantasise about doing it as an real-life footballer, but when you pursue a career in this job and there is an chance to represent England, putting the shirt on is something special.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"For me he is the best player in the world so defeating him in a tournament like this just provides a massive injection of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were impressive against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and it seemed this is it, they could potentially be title contenders.
Since then, however, they were beaten physically by Leeds, looked flat against Bournemouth and this week got turned over by Atalanta in the Champions League.
So head coach Enzo Maresca is in need of a win here to return to winning ways, but it will be a challenge because Everton are such a dangerous team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing exceptionally and they have got a bit of a positive run at the moment.
On form you would likely back the visitors, while the most logical prediction would likely be a draw, but I am not going to be sensible.
They have not given me any good cause to back them recently, but I just have a feeling Chelsea will win this match because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be fascinating to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the stuff with Mohamed Salah this week.
Slot should not have to put up with that drama. I know Salah has been a great for the club but essentially Slot just wants to win games and there is no bias in his team selection.
They changed their tactical setup against Inter and went with a midfield diamond and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he makes amends.
Slot's primary concern will be on winning this game, but it is a tough one.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
Sunderland have had the opportunity to rest while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Apart from their superb performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, especially straight after they've played in the Champions League.
It is anticipated that that pattern to continue on Sunday, and their tiredness is likely to be a significant issue in how this game goes because of Sunderland's energetic style.
We saw how incessant Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays in midfield with him, has also been one of the top transfers and warrants praise too.
I am expecting this being the best game|most exciting fixture
